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TRICYCLIC ANTIDEPRESSANTS (TCA) |
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 TCA (Tricyclic Antidepressants) are
commonly used for the treatment of depressive disorders. TCA overdoses can
result in profound central nervous system depression, cardiotoxicity and
anticholinergic effects. TCA overdose is the most common cause of death from
prescription drugs. TCAs are taken orally or sometimes by injection. TCAs are
metabolized in the liver. Both TCAs and their metabolites are excreted in urine
mostly in the form of metabolites for up to ten days.
The
DRUGCHECK® Drug of Abuse Test yields a positive result when the
concentration of Tricyclic Antidepressants in urine exceeds 1,000 ng/mL. |
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