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PHENCYCLIDINE (PCP) |
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 Phencyclidine, also known as PCP or
Angel Dust, is a hallucinogen that was first marketed as a surgical anesthetic
in the 1950's. It was removed from the market because patients receiving it
became delirious and experienced hallucinations.
Phencyclidine is used
in powder, capsule, and tablet form. The powder is either snorted or smoked
after mixing it with marijuana or vegetable matter. Phencyclidine is most
commonly administered by inhalation but can be used intravenously,
intranasally, and orally. After low doses, the user thinks and acts swiftly and
experiences mood swings from euphoria to depression. Self-injurious behavior is
one of the devastating effects of Phencyclidine.
PCP can be found in
urine within 4 to 6 hours after use and will remain in urine for 7 to 14 days,
depending on factors such as metabolic rate, user's age, weight, activity, and
diet. Phencyclidine is excreted in the urine as an unchanged drug (4% to 19%)
and conjugated metabolites (25% to 30%).
The DRUGCHECK® Drug of
Abuse Test yields a positive result when the phencyclidine level in urine
exceeds 25 ng/mL. This is the suggested screening cut-off for positive
specimens set by the Substance Abuse and Mental Health Services Administration
(SAMHSA, USA).
NOTE: Effexor Tablets (venlafaxine hydrochloride)
a treatment for depressive, anxiety and social disorder have shown to cause
false positive urine results for Phencyclidine (PCP). Positive urine screening
should always be confirmed by GCMS. |
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