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METHAMPHETAMINE (MET) |
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 Methamphetamine is an addictive
stimulant drug that strongly activates certain systems in the brain.
Methamphetamine is closely related chemically to amphetamine, but the central
nervous system effects of Methamphetamine are greater. Methamphetamine is made
in illegal laboratories and has a high potential for abuse and dependence. The
drug can be taken orally, injected, or inhaled. Acute higher doses lead to
enhanced stimulation of the central nervous system and induce euphoria,
alertness, reduced appetite, and a sense of increased energy and power.
Cardiovascular responses to Methamphetamine include increased blood pres- sure
and cardiac arrhythmias. More acute responses produce anxiety, paranoia,
hallucinations, psychotic behavior, and eventually, depression and exhaustion.
The effects of Methamphetamine generally last 2-4 hours and the drug has a
half-life of 9-24 hours in the body. Methamphetamine is excreted in the urine
as amphetamine and oxidized and delaminated derivatives. However, 10-20% of
Methamphetamine is excreted unchanged. Thus, the presence of the parent
compound in the urine indicates Methamphetamine use. Methamphetamine is
generally detectable in the urine for 3-5 days, depending on urine pH level.
The DRUGCHECK® Drug of Abuse Test yields a positive result when the
Methamphetamine in urine exceeds 1,000 ng/mL. |
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