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BENZODIAZEPINES (BZD) |
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Benzodiazepines are medications
that are frequently prescribed for the symptomatic treatment of anxiety and
sleep disorders.They produce their effects via specifc receptors involving a
neurochemical called gamma aminobutyric acid (GABA). Because they are safer and
more effective, Benzodiazepines have replaced barbiturates in the treatment of
both anxiety and insomnia.
Benzodiazepines are also used as sedatives
before some surgical and medical procedures, and for the treatment of seizure
disorders and alcohol withdrawal.
Risk of physical dependence increases
if Benzodiazepines are taken regularly (e.g., daily) for more than a few
months, especially at higher than normal doses. Stopping abruptly can bring on
such symptoms as trouble sleeping, gastrointestinal upset, feeling unwell, loss
of appetite, sweating, trembling, weakness, anxiety and changes in perception.
Only trace amounts (less than 1%) of most Benzodiazepines are excreted
unaltered in the urine; most of the concentration in urine is conjugated drug.
The detection period for the Benzodiazepines in the urine is 3-7 days.
The DRUGCHECK® Drug of Abuse Test yields a positive result when the
Benzodiazepines in urine exceed 300 ng/mL. |
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