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BARBITURATES (BAR)

Barbiturates produce a wide spectrum of central nervous system depression, from mild sedation to coma, and have been used as sedatives, hypnotics, anesthetics, and anticonvulsants. Barbiturates are classified as ultrashort, short, intermediate, and long-acting. These drugs are primarily used for insomnia and preoperative sedation daytime sedation and the treatment of seizure disorders. Veterinarians use pentobarbital, a long-acting barbiturate, for anesthesia and euthanasia.

Barbiturates are common drugs of abuse taken orally or intravenously. They produce symptoms similar to intoxication. Chronic use will develop tolerance, physical dependence and psychological dependence on barbiturates. Overdoses can cause profound shock, coma, or death.

Shorter acting barbiturates (Allobarbital, Alphenal, Amobarbital, Aprobarbital, Butabarbital, Butalbital, Butethal, Pentobarbital, Secobarbital) can be detected for only 1 to 4 days, while long-acting barbiturates (Barbital, Phenobarbital) can be detected for 2 to 3 weeks. Normally the suggested detection period for the Barbiturates in urine is 4 to 7 days.

The DRUGCHECK® Drug of Abuse Test yields a positive result when the Barbiturates (Secobarbital) in urine exceed 300 ng/mL.
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